The Mediterranea sea18 column represents the latest generation of HPLC columns. This column is designed to excel in retaining polar compounds within a 100% aqueous environment, all while avoiding the issues of unwanted interactions commonly associated with inefficiently endcapped conventional packings.
The packing chemistry is based on the new MED technology, known as "multifunctional endcapping deactivated." This technology achieves remarkable levels of deactivation, resistance to extreme pH values, and versatility in chromatographic applications, surpassing what conventional or polar-embedded reverse phase packings can offer.
The MED technology has been meticulously developed to ensure maximum reproducibility, aiming for chromatographic separations that are consistent from column to column.
To create the world's best reverse phase packing, it is imperative to start with extremely pure silica. The silica particle forming the foundation of the Mediterranea sea18 packing is derived from ultra-pure materials and undergoes stringent manufacturing processes to eliminate any possibility of contamination. The Mediterranea sea18 silica particle has been meticulously optimized across various processing factors, resulting in a perfectly spherical, rigid, and inert particle with exceptionally low metal content. This nearly metal-free composition is one of the key factors contributing to the exceptional properties of the Mediterranea sea18 column.